Director, Software Engineering - Product Integration

Natera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. As we scale our life-saving diagnostics, we are transforming our approach to software quality and reliability.

We are seeking a seasoned and visionary Director of Engineering, Product Integration to lead a newly formed Product Integration team. You will pivot our strategy from traditional, late-stage configuration testing to a proactive, end-to-end integration function that de-risks our most complex "Pillar" projects (eg, LCGP, Signatera IVD).

This role requires a leader who is AI-native, hands-on, and high agency. You will not just manage a team; you will act as the "Integration Quarterback" for the engineering organization, defining the "Golden Paths" through our distributed architecture and driving an incremental, milestone-based validation strategy. You will live the ethos of agile, user-centered development, using modern tools to create massive leverage and ensure our software works seamlessly from order to report.

Key Responsibilities Strategic Leadership & Vision

• Transform Integration Strategy: Lead the transition from the Legacy "PSPC" model to a modern, risk-based integration strategy. Define a vision where testing is not a bottleneck but a continuous, value-added activity Embedded in the development lifecycle.
• High Agency Execution: Champion a culture of urgency and ownership. Proactively identify integration risks during the design phase (shifting left) rather than waiting for code freeze.
• AI-Native Leverage: Pioneer the use of AI and LLMs to revolutionize testing. Implement strategies to auto-generate test cases from PRDs, use AI for intelligent log analysis and root cause detection, and dramatically increase team throughput.

Product Integration & Execution

• "Quarterback" Model: Serve as the integration lead for major company initiatives. Partner with Solution Architects to define "Integration Milestones" and extract iterative builds from component teams to validate workflows progressively.
• End-to-End Ownership: Own the validation of critical business workflows across the full stack (Portal ? LIMS ? Lab Execution ? Bioinformatics ? Reporting). Ensure that the "Happy Path" is unbreakable and that unhappy paths are supported.
• User-Centered Validation: Go beyond spec compliance to verify the user experience. Ensure that the integrated system delivers the intended value to clinicians and patients, using realistic data that mirrors production complexity.
• Environment Strategy: Act as the gatekeeper for the Staging/Integration environments. Enforce strict configuration management and version control to ensure our test beds accurately reflect Production reality.
• Build a High-Performance Team: Recruit and mentor a new breed of "Integration Leads"-technical, code-savvy individuals who understand microservices architecture and business logic equally well.
• Foster Innovation: Create an environment where the team is encouraged to experiment with new tools (eg, chaos engineering, AI agents) to break the system before our users do.

Qualifications

• 10+ years of engineering experience, with at least 5 years in leadership roles managing complex software integration, QA, or SDET teams.
• Deep Technical Expertise: Strong background in testing distributed systems, microservices, and event-driven architectures (Kafka, AWS). You understand that "integration" means API contracts, data consistency, and system resilience.
• Transformation Experience: Proven track record of turning around underperforming testing functions or building "Zero-to-One" quality organizations in a rapid-growth environment.
• Regulated Industry Experience: Familiarity with healthcare standards (HIPAA, CLIA, FDA) is strongly preferred, but a demonstrated ability to bring rigor to complex regulated environments is essential.
• BS/MS in Computer Science, Engineering, or a related field.

Knowledge, Skills, and Abilities

• User-Centered: You obsess over the end-user experience. You understand that a passing API test is meaningless if the clinician can't view the report.
• High Agency: You don't wait for permission to fix broken processes. You navigate ambiguity with confidence and drive cross-functional alignment.
• Technical Fluency: Ability to go deep with architects on API schema design and equally deep with product managers on user journey mapping.

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

Position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:

• Annual performance incentive bonus
• Long-term equity awards
• 401(k) with company match
• Generous paid time off and company holidays
• Additional wellness and work-life benefits

Compensation Range
$171,400 - $214,300 USD

Our Opportunity

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

What We Offer

Competitive benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401(k) benefits, commuter benefits and much more. We also offer a generous employee referral program!

Equal Opportunity Employer

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Natera's Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

• "Disabled veteran": a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
• "Recently separated veteran": any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
• "Active duty wartime or campaign badge veteran": a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
• "Armed forces service medal veteran": a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress toward this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your "major life activities." If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

• Alcohol or other substance use disorder (not currently using drugs illegally)
• Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
• Blind or low vision
• Cancer (past or present)
• Cardiovascular or heart disease
• Celiac disease
• Cerebral palsy
• Deaf or serious difficulty hearing
• Diabetes
• Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
• Epilepsy or other seizure disorder
• Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
• Intellectual or developmental disability
• Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
• Missing limbs or partially missing limbs
• Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
• Nervous system condition, for example, migraine headaches, Parkinson's disease, multiple sclerosis (MS)
• Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
• Partial or complete paralysis (any cause)
• Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
• Short stature (dwarfism)
• Traumatic brain injury

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.